Table 3 The three top gene ontology terms identified to be associated with gene-clusters in DAVID.

From: Profiling of the microRNA transcriptome in feline whole blood

miRNA

ES > 2.0

GO-terminology

GO-category

let-7c-5p

2.24

cellular response to amino acid stimulus;

extracellular matrix structural constituent;

endoplasmic reticulum lumen

BP;

MF;

CC

miR-26b-5p

3.03

protein phosphorylation;

protein serine/threonine kinase activity;

ATP binding

BP;

MF;

MF

 

2.25

Wnt signalling pathway, calcium modulating pathway;

posttranscriptional gene silencing by RNA;

miRNA mediated inhibition of translation

BP;

BP;

BP

 

2.07

negative regulation of pancreatic juice secretion;

positive regulation of ion transmembrane transporter activity;

regulation of ion homeostasis

BP;

BP;

BP

miR-98-5p

2.23

cellular response to amino acid stimulus;

extracellular matrix structural constituent;

endoplasmic reticulum lumen

BP;

MF;

CC

miR-204-5p

3.60

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding;

positive regulation of transcription from RNA polymerase II promoter;

transcription from RNA polymerase II promoter

BP;

MF;

MF

  1. Data is presented for miRNAs that have clusters with an enrichment score (ES) > 2.0. Results are based on human based gene-target lists. GO = gene ontology; BP = biological process; MF = molecular function; CC = cellular compartment.