Fig. 12 | Scientific Reports

Fig. 12

From: Design of a multi-Epitope mRNA vaccine against Brucella type IV secretion system using reverse vaccinology and immunogenicity approaches

Fig. 12

The immune simulation conducted after three injections. A: Antibody production increased with each injection, with IgM + IgG levels. B: B cell counts following each vaccine injection exhibited an upward trend. C: The counts of helper T cells. D: The counts of cytotoxic T cells. E: The number of NK cells in three injections; F: The number of DC cells in three injections; G: The number of macrophages in three injections; H: Changes in epithelial cells across three injections; I: Changes in cytokines across three injections.

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