Table 2 Presents the antigenicity, allergenicity, and toxicity of the final selected CTL dominant epitopes.

From: Design of a multi-Epitope mRNA vaccine against Brucella type IV secretion system using reverse vaccinology and immunogenicity approaches

 

Peptide

Allele

Peptide length

Start

End

Antigenicity

Allergenicity

Toxicity

VirB2

SIAAIEPNL

HLA-A*02:01

9

25

33

1.2654

NON-ALLERGEN

Non-Toxin

VirB3

AMLFGVPVI

HLA-A*02:01

9

28

36

0.4653

NON-ALLERGEN

Non-Toxin

 

ILPLIVPIV

HLA-A*02:01

9

56

64

1.4522

NON-ALLERGEN

Non-Toxin

VirB6

SISSAIFSR

HLA-A*11:01

9

224

232

0.4543

NON-ALLERGEN

Non-Toxin

BtpA

VLSEHFFSK

HLA-A*03:01

9

178

186

0.6603

NON-ALLERGEN

Non-Toxin

 

KVALNTSLK

HLA-A*03:01

9

229

237

0.7452

NON-ALLERGEN

Non-Toxin

 

ALNTSLKSV

HLA-A*02:01

9

231

239

0.7004

NON-ALLERGEN

Non-Toxin