Fig. 1
From: Contribution of reversible histone acetylation to freeze tolerance and recovery in wood frog kidneys
A reversible process of acetylation and deacetylation initiated by the freeze/thaw cycle. HAT (KATs) acetylates lysine in the presence of acetyl co-A to open up the chromatin thereby initiating transcription. On the other hand, HDACs deacetylates histone tails thereby causing a closed chromatin and inhibiting transcription.
