Fig. 3

Schematic diagram of the HDMI image processing pipeline. A sequence of high-frame-rate ultrasound (US) data is acquired. Following clutter removal using singular value decomposition (SVD), background noise is suppressed, and vessel enhancement filtering is applied to generate the final HDMI image18. The Morphological Filtering and Vessel Segmentation Module then converts the enhanced image into a binary format, extracts the vessel skeleton, and identifies individual vessel structures that are prepared for quantification21.