Table 4 Multivariable logistic regression analysis of long-COVID risk factors: adjusted odds ratios for demographic, clinical, and symptom-based predictors.

From: A multinational cross-sectional study on the prevalence and predictors of long COVID across 33 countries

Parameter

(OR 95% CI; P value)

Age

1.01 (1, 1.01; P ≤ 0.001)

Female sex

1.80 (1.61, 2.02; P ≤ 0.001)

BMI

1.01 (1, 1.02; P = 0.128)

Ethnicity

 White/Caucasian

Ref

 Hispanic or Latino

1.53 (1.26, 1.85; P ≤ 0.001)

 Middle eastern

0.94 (0.83, 1.06; P = 0.3)

 Black or African American

0.37 (0.29, 0.47; P ≤ 0.001)

 Asian

0.50 (0.42, 0.59; P ≤ 0.001)

 Indian

0.68 (0.52, 0.88; P = 0.004)

 Other

0.77 (0.63, 0.93; P = 0.008)

Smoking

 Non-Smoker

Ref

 Current Smoker

0.71 (0.53, 0.95; P = 0.022)

 Ex-smoker

0.93 (0.7, 1.22; P = 0.619)

Smoking duration (Years)

1.06 (0.99, 1.15; P = 0.11)

Number of cigarettes

1.00 (0.99, 1.01; P = 0.996)

Respiratory parameters

 Anosmia

0.92 (0.8, 1.05; P = 0.214)

 Asthma

1.01 (0.84, 1.2; P = 0.942)

 Chest pain

1.33 (1.17, 1.51; P ≤ 0.001)

 Cough

0.85 (0.77, 0.95; P = 0.003)

 Runny nose

0.81 (0.73, 0.91; P ≤ 0.001)

 SOB

1.43 (1.28, 1.6; P ≤ 0.001)

 Sore throat

1.02 (0.92, 1.14; P = 0.659)

Constitutional and neurologic

 Confusion

1.03 (0.86, 1.23; P = 0.748)

 Conjunctivitis

0.68 (0.53, 0.87; P = 0.002)

 Dysgeusia

1.41 (1.26, 1.59; P ≤ 0.001)

 Fatigue

1.60 (1.43, 1.78; P ≤ 0.001)

 Fever

0.86 (0.77, 0.96; P = 0.005)

 History stroke

0.82 (0.48, 1.35; P = 0.446)

 Migraine

1.30 (1.13, 1.49; P ≤ 0.001)

 Muscle joint

1.44 (1.29, 1.61; P ≤ 0.001)

 Rash

0.77 (0.61, 0.97; P = 0.028)

 GI symptoms

1.04 (0.94, 1.16; P = 0.424)

 Insomnia

1.15 (0.97, 1.35; P = 0.116)

Comorbidities

 Anemia

0.77 (0.63, 0.93; P = 0.008)

 Autoimmune disease

1.04 (0.84, 1.3; P = 0.693)

 Cancer

1.35 (0.78, 2.24; P = 0.266)

 COPD

1.30 (0.81, 2.04; P = 0.268)

 Type 1 diabetes

0.75 (0.49, 1.13; P = 0.181)

 Type 2 diabetes

0.87 (0.66, 1.14; P = 0.318)

 Immunosuppression

0.86 (0.64, 1.15; P = 0.325)

 GI disease

1.48 (1.22, 1.8; P ≤ 0.001)

 Heart disease

0.73 (0.54, 0.98; P = 0.041)

 Hypertension

0.92 (0.76, 1.1; P = 0.358)

 Renal disease

1.19 (0.75, 1.85; P = 0.439)

 Seizure

0.89 (0.53, 1.43; P = 0.634)

Isolation

 No Isolation

Ref

 Home isolation

1.22 (0.92, 1.65; P = 0.171)

 Hospital isolation in floor

1.08 (0.76, 1.53; P = 0.672)

 Hospital isolation in ICU department

2.08 (1.36, 3.18; P = 0.001)

Reinfection

1.20 (1.07, 1.34; P = 0.002)

Received one or more doses of COVID vaccine

0.62 (0.54, 0.71; P ≤ 0.001)

  1. OR, Odds Ratio; CI, Confidence Interval; BMI, Body Mass Index; SOB, Shortness of Breath; GI, Gastrointestinal; COPD, Chronic Obstructive Pulmonary Disease; Ref, Reference variable.