Fig. 9 | Scientific Reports

Fig. 9

From: TIPE2 combined with immune cell infiltration predicts prognosis in colorectal cancer

Fig. 9The alternative text for this image may have been generated using AI.

Correlation analysis between TIPE2, CD8, and T cell exhaustion markers PD-1 and TIM-3. (A, B) TIPE2 protein expression was positively correlated with PD-1 (A) and TIM-3 (B) in CRC tissues, as determined by IHC staining and semi-quantitative scoring. (C, D) CD8⁺ T cell infiltration was also positively associated with PD-1 (C) and TIM-3 (D) expression. (E–H) Transcriptomic correlation analyses using the GEPIA database confirmed that PD-1 and TIM-3 mRNA levels were positively correlated with both TIPE2 (E, F) and CD8 (G, H) expression in CRC.

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