Fig. 3

Ciprofloxacin-loaded mucosomes can be freeze-dried and stored before being used. No differences in terms of antibacterial efficacy were found for (a) P. aeruginosa and (b) S. aureus, when comparing the survival rate of the cultures to freeze-dried and rehydrated ciprofloxacin-loaded mucosomes, ciprofloxacin-loaded mucosomes, and free ciprofloxacin. The concentrations of active principle used for this experiment were chosen as the minimum concentration employed in this work, the MIC of ciprofloxacin according to the EUCAST database, and the maximum concentration among those used in this work at which all the treatments showed the same efficacy on both bacterial strains.