Fig. 6

Mucosomes enhance the delivery of ciprofloxacin through a mucus-like interface. (a) Schematization of the experimental set-up. (b) When ciprofloxacin was loaded into mucosomes, the presence of a mucus-mimicking interface did not alter its diffusion into the acceptor compartment. The survival rate of (c) P. aeruginosa and (d) S. aureus significantly decreases (p < 0.001 for P. aeruginosa and p < 0.00001 for S. aureus) when the cultures are treated with ciprofloxacin-loaded mucosomes, compared to free ciprofloxacin.