Fig. 1
Tig1 and Prod1 overexpression elicits cell-autonomous displacement toward proximal regions during axolotl limb regeneration. Time series representing the displacement assay using control, Tig1 and Prod1 overexpression experimental conditions (columns). Images were taken at 1, 7, 12, 18 and 24 days post-electroporation (dpe) (rows). Despite their initial localization in the distal-most blastema compartment, control-electroporated cells remain at the distal region of the regenerating limb, while both Tig1 and Prod1-transfected cells can shift their position towards more proximal locations along the regenerate. Asterisk indicates unspecific autofluorescence in the trunk. Scale bar = 1 mm.
