Fig. 6
Proximalisation velocity is consistent with the proximalisation force derived from a spatially dependent potential. (A) Electroporated cells in the most distal region of the blastema at 1 day post electroporation (dpe): when only Gfp is electroporated (control, red), a spatially uniform proximalisation potential is generated. In contrast, electroporation of Tig1 or Prod1 (green) results in a non-uniform proximalisation potential. (B) Electroporated cells at 24 dpe: the proximalisation potential is constant for control cells (red), which motivates zero proximalisation force, forcing the cells to remain distally where they were electroporated. In contrast, the cells overexpressing Tig1 and Prod1 (green) experience a spatially dependent proximalisation potential that triggers a proximalisation force that induces their movement towards proximal regions.
