Fig. 5
From: Shared genomic features of HIV+ diffuse large B-cell lymphoma in two African cohorts
Evidence of microsatellite-instability among HIV + DLBCL. (A) Tumor mutational burden (TMB) by continuous microsatellite instability (MSI) metric using Pearson correlation. Dotted line indicates MSI-high (step-wise difference ≥ 0.4). Shape indicates cohort and color indicates HIV/ART status. n = 46, samples with known HIV/ART status. (B) Lollipop plot of PMS2 mutations. C) Lollipop plot of ARID1A mutations. (B, C) All labelled variants occurred at a VAF > 10% and were predicted to have an effect.
