Table 1 Comparison of patient characteristics between the non-triple-negative breast cancer (TNBC) and TNBC groups.
Characteristics | Total (n = 469) | non-TNBC (n = 238) | TNBC (n = 231) | p-value |
|---|---|---|---|---|
Age (yr) (Mean ± SD) | 47.35 ± 9.12 | 47.24 ± 8.98 | 47.46 ± 9.28 | 0.999 |
Breast operation | 0.001 | |||
Breast-conserving surgery | 292(62.4) | 131(55.0) | 161(70.0) | |
Total mastectomy | 176(37.6) | 107(45.0) | 69(30.0) | |
Unknown | 1 | 0 | 1 | |
Axillary operation | 0.322 | |||
No | 2(0.4) | 2(0.8) | 0(0.0) | |
Sentinel node biopsy | 67(14.3) | 36(15.1) | 31(13.4) | |
Axillary lymph node dissection | 400(85.3) | 200(84.0) | 200(86.6) | |
pT stage | 0.015 | |||
T0/is | 4(0.9) | 0(0.0) | 4(1.7) | |
T1 | 178(38.0) | 105(44.1) | 73(31.6) | |
T2 | 254(54.2) | 115(48.3) | 139(60.2) | |
T3 | 30(6.4) | 16(6.7) | 14(6.1) | |
T4 | 3(0.6) | 2(0.8) | 1(0.4) | |
pN stage | 0.412 | |||
N0 | 7(1.5) | 4(1.7) | 3(1.3) | |
N1 | 326(69.5) | 167(70.2) | 159(68.8) | |
N2 | 388(17.5) | 45(18.9) | 37(16.0) | |
N3 | 360(11.5) | 22(9.2) | 32(13.9) | |
Pathologic stage | 0.992 | |||
I | 17(3.6) | 8(3.4) | 9(3.9) | |
II | 298(63.5) | 152(63.9) | 146(63.2) | |
III | 152(32.4) | 77(32.4) | 75(32.5) | |
IV | 2(0.4) | 1(0.4) | 1(0.4) | |
ER | - | - | ||
Negative | 54(22.7) | 54(22.7) | - | - |
Positive | 184(77.3) | 184(77.3) | - | - |
PGR | - | - | ||
Negative | 93(39.1) | 93(39.1) | - | - |
Positive | 145(60.9) | 145(60.9) | - | - |
HER2 status | - | - | ||
Negative | 148(66.7) | 148(66.7) | - | - |
Positive | 74(33.3) | 74(33.3) | - | - |
Unknown | 16 | 16 | - | - |
Histologic grade | < 0.001 | |||
G1/2 | 195(41.8) | 154(64.7) | 41(18.0) | |
G3 | 271(58.2) | 84(35.3) | 187(82.0) | |
Unknown | 3 | 0 | 3 | |
Nuclear grade | < 0.001 | |||
G1/2 | 191(41.0) | 151(63.4) | 40(17.5) | |
G3 | 275(59.0) | 87(36.6) | 188(82.5) | |
Unknown | 3 | 0 | 3 | |
Lymphovascular invasion | 0.539 | |||
Absent | 276(60.3) | 139(58.9) | 137(61.7) | |
Present | 182(39.7) | 97(41.1) | 85(38.3) | |
Unknown | 11 | 2 | 9 | |
P53 | < 0.001 | |||
Negative | 275(59.1) | 168(71.5) | 107(46.5) | |
Weak | 31(6.7) | 21(8.9) | 10(4.3) | |
Intermediate | 25(5.4) | 11(4.7) | 14(6.1) | |
Strong | 134(28.8) | 35(14.9) | 99(43.0) | |
Unknown | 4 | 3 | 1 | |
Ki-67 | < 0.001 | |||
Low (≤ 20%) | 72(35.5) | 54(56.8) | 18(16.7) | |
High(> 20%) | 131(64.5) | 41(43.2) | 90(83.3) | |
Unknown | 266 | 143 | 123 | |
Radiotherapy | 0.010 | |||
No | 98(20.9) | 61(25.6) | 37(16.0) | |
Yes | 371(79.1) | 177(74.4) | 194(84.0) |
