Fig. 3
Quantification of the relative amount of (a) cellular lipids based on SD second derivative FTIR signals for the total lipids [1], cholesterol [2], esterified lipids [3], and acyl chain length [4]; (b) cellular proteins based on SD second derivative FTIR signals for the total proteins [1] and conformational changes [2]; (c) lipids in LDs based on Raman signals for the number of lipid droplets [1] and their unsaturation [2]; (d) proteins and lipids in PA based on Raman signals for protein cross-linking [1] and lipids [2]. The parameters of the spectral markers are given in Table 1. One-way ANOVA or non-parametric Kruskal–Wallis ANOVA analysis were used to determine to calculated statistical significance at p-value thresholds of *p < 0.05, **p < 0.01, and ***p < 0.001.
