Fig. 3 | Scientific Reports

Fig. 3

From: Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea

Fig. 3

Spatiotemporal genomic surveillance of the Orthohantavirus hantanense (HTNV) S segment in the Republic of Korea (ROK). (A–D) Comprehensive phylodynamic analyses of the HTNV S segment across the ROK between 1976 and 2023. (A) A time-scaled phylogenetic tree reconstructed using TimeTree, focusing on the HTNV S segment (positions 1–1,696 nt). (B) The geographic distribution of HTNV genomes, with colored circles indicating the population size at each collection site (village level). (C) The genomic diversity and entropy within both nucleotide and amino acid sequences of the HTNV S segment. (D) The frequency patterns of HTNV lineages circulating in the ROK over the study period, with each lineage in the study denoted by a unique colored symbol.

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