Fig. 2

SARS-CoV-2 S and VSV-G pseudotyped VLP entry into Calu3 KO cells. (A) SARS-CoV-2 pseudotyped VLP entry in Calu3 cells transduced with lentiviral CRISPR/Cas9 guide RNAs (2 per target). ACE2 was used as a positive control. (B) VSV-G pseudotyped VLP entry in Calu3 cells transduced with lentiviral CRISPR/Cas9 guide RNAs (2 per target). The results are shown in fold change to control in relative light units. P values were calculated with Brown Forsythe and Welch ANOVA (* < 0.05, ** < 0.01, *** < 0.001).