Fig. 1 | Scientific Reports

Fig. 1

From: Interfering with USP50 expression inhibits macrophage pyroptosis in sepsis-induced acute lung injury by degrading NLRP3 protein

Fig. 1

USP50 is highly expressed in patients with sepsis-induced ARDS and CLP-induced mice. (A) USP50 expression was measured in patients with sepsis-induced ARDS (n = 48) and healthy controls (n = 35) using qPCR. (B) Patients with sepsis-induced ARDS were divided into USP50 high (fold ≥ 2; n = 28) and low (fold < 2; n = 20) expression groups, and the overall survival was calculated. (C) The diagnostic value of USP50 was analysed using the ROC curve. (D) USP50 expression was measured using qPCR in the lung tissues of mice in the sham and CLP groups (n = 6). (E) USP50 expression was measured in the blood of mice using qPCR in the sham and CLP groups (n = 6). **P < 0.01.

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