Fig. 6
From: A digital plating platform for robust and versatile microbial detection and analysis
Phenotyping antibiotic resistance using the DP platform. (A) Representative bright-field microimages showing E. coli microcolonies grown in the PicoArray chips under different concentrations of ampicillin sodium after 6 h of incubation at 37 ºC. Initial concentration of E. coli ~ 1 × 105 CFU/mL. (B) Dose response curve for E. coli viability after treatment with different concentrations of ampicillin sodium. Calculation of MIC using a Gompertz function fit. Blue vertical dashed line shows the position of the MIC. Each test was performed in triplicate (n = 3). Error bars represent standard deviation (SD). (C) Representative bright-field microimages showing the morphology changes of E. coli under antibiotic stress.
