Fig. 2

Toxicity analysis of amatoxin. (A) Two-dimensional structure of amatoxin. (B) The Predicted LD50 of amatoxin was 73Â mg/kg, the Predicted Toxicity Class was 3, the Average similarity was 49.45%, and the Prediction accuracy was 54.26%. (C) Amatoxin can cause strong human hepatotoxicity as well as strong drug-induced liver injury and respiratory toxicity.