Fig. 5

SEM images of MRSA clinical isolate MB-1137. (a) Untreated control cells exhibiting normal morphology; (b) Cells treated with citral, demonstrating structural alterations indicative of membrane disruption; (c) Cells treated with azithromycin, showing characteristic changes associated with antibiotic action; (d) Cells treated with the citral-azithromycin combination at ½ MIC concentration, revealing pronounced morphological damage. These images illustrate the differential effects of treatments on bacterial cell integrity, highlighting the potential synergistic action of the citral-azithromycin combination.