Table 2 Univariate and multivariate analyses of variables related to HF.

Sex

Female

Reference

Male

1.246

[0.849,1.829]

0.261

Age

<65

Reference

Reference

≥ 65

9.837

[6.399,15.123]

<0.001

3.329

[1.304,8.83]

BMI

<25 kg/m²

Reference

Reference

≥ 25 kg/m²

3.84

[2.596,5.680]

<0.001

3.616

[1.48,9.199]

ASA

<3

Reference

≥ 3

0.966

[0.661,1.414]

0.860

Drinking history

No

Reference

Reference

Yes

3.927

[2.651,5.816]

<0.001

2.336

[0.972,5.683]

Smoking history

No

Reference

Reference

Yes

7.864

[5.220,11.846]

<0.001

9.834

[2.467,47.594]

Surgical history

No

Reference

Yes

1.128

[0.769,1.654]

0.538

Anemia

No

Reference

Yes

1.118

[0.734,1.704]

0.603

Hyperlipidemia

No

Reference

Reference

Yes

6.539

[4.360,9.807]

<0.001

4.906

[2.043,12.286]

Hypertension

No

Reference

Reference

Yes

7.415

[4.920,11.175]

<0.001

5.565

[2.307,14.306]

Diabetes

No

Reference

Reference

Yes

5.325

[3.575,7.933]

<0.001

10.564

[4.197,29.318]

Preoperative tachycardia

No

Reference

Reference

Yes

4.026

[2.719,5.961]

<0.001

6.481

[2.666,16.979]

COPD

No

Reference

Reference

Yes

4.377

[2.950,6.494]

<0.001

4.456

[1.804,11.575]

CKD

No

Reference

Yes

1.248

[0.766,2.033]

0.373

T-stage

T1 ~ T2

Reference

Reference

T3 ~ T4

4.036

[2.688,6.061]

<0.001

2.496

[0.963,6.551]

N-stage

N0

Reference

Reference

N1 ~ N2

4.401

[2.952,6.561]

<0.001

2.832

[1.085,7.608]

Adjuvant Radiotherapy

No

Reference

Yes

1.545

[0.981,2.434]

0.060

Adjuvant Chemotherapy

No

Reference

Yes

0.949

[0.622,1.448]

0.808

Surgical procedure

Laparoscopic surgery

Reference

Open surgery

0.781

[0.534,1.143]

0.203

Emergency surgery

No

Reference

Yes

0.991

[0.656,1.497]

0.965

Lymph node dissection

<12

Reference

≥ 12

0.771

[0.505,1.178]

0.230

Surgery time

<270 min

Reference

Reference

≥ 270 min

4.858

[3.264,7.230]

<0.001

1.572

[0.361,6.385]

Intraoperative bleeding

<100 ml

Reference

Reference

≥ 100 ml

5.704

[3.791,8.583]

<0.001

1.811

[0.722,4.598]

Blood transfusion

No

Reference

Reference

Yes

8.786

[5.806,13.295]

<0.001

10.438

[4.288,27.675]

Intraoperative tachycardia

No

Reference

Reference

Yes

4.982

[3.332,7.449]

<0.001

8.435

[3.466,22.614]

Tumor number

<2

Reference

≥ 2

1.081

[0.672,1.742]

0.747

Tumor size

<5 cm

Reference

Reference

≥ 5 cm

2.507

[1.591,3.951]

<0.001

2.351

[0.749,7.263]

CEA level

<5 ng/ml

Reference

≥ 5 ng/ml

1.17

[0.735,1.863]

0.507

CA19-9 level

<37 U/mL

Reference

≥ 37 U/mL

0.728

[0.449,1.182]

0.199

PCT level

<0.05 ng/ml

Reference

≥ 0.05 ng/ml

1.148

[0.773,1.704]

0.494

CRP level

<10 mg/l

Reference

Reference

≥ 10 mg/l

4.396

[2.952,6.546]

<0.001

3.556

[1.473,9.105]

SAA level

<10 mg/l

Reference

≥ 10 mg/l

0.986

[0.674,1.441]

0.940

NLR

<3

Reference

Reference

≥ 3

3.089

[2.096,4.553]

<0.001

3.842

[1.617,9.621]

ALB

≥ 30 g/L

Reference

Reference

<30 g/L

2.821

[1.895,4.200]

<0.001

1.43

[0.583,3.487]

NRS2002 score

<3

Reference

≥ 3

0.786

[0.506,1.222]

0.286

Disease duration

<6 months

Reference

≥ 6 months

1.126

[0.741,1.710]

0.578