Fig. 2 | Scientific Reports

Fig. 2

From: Potential utility of salivary gland amyloid uptake as a surrogate marker for adipose tissue and amyloid-beta dynamics based on its association with BMI and cerebral amyloid burden

Fig. 2

Correlations between BMI, SUVRB, SUVRSG, and VolSG. (A) Body mass index (BMI) was significantly negatively correlated with SUVRB (r = − 0.247, p = 0.0009), suggesting that individuals with higher BMI tend to have lower cerebral amyloid deposition. (B) BMI showed a significant positive correlation with SUVRSG (r = 0.231, p = 0.0019), indicating that increased peripheral adipose metabolism may be linked to higher amyloid uptake in the salivary glands. (C) SUVRSG was negatively correlated with SUVRB (r = − 0.188, p = 0.0102), supporting the hypothesis that amyloid sequestration in peripheral tissues may be associated with lower cerebral amyloid burden. (D) BMI exhibited a strong positive correlation with salivary gland volume (VolSG) (r = 0.469, p < 0.001), consistent with previous findings that salivary gland fat content increases with BMI. Pearson correlation analysis was used for statistical comparisons.

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