Table 4 Quality of ulcer healing at 8 weeks after ESD.

From: Comparison of rebamipide and tegoprazan combination therapy and tegoprazan monotherapy for ESD induced gastric ulcers a randomized multicenter study

 

Combination therapy (n = 64)

Tegoprazan monotherapy

(n = 68)

P value

Kappa value

Quality of ulcer healing at week 8*

Reviewer 1

  

0.02

0.862

 Flat

46 (75.4%)

33 (51.6%)

  

 Nodular

11 (18.0%)

22 (34.4%)

  

 Intermediate

4 (6.6%)

9 (14.1%)

  

Reviewer 2

  

0.002

 

 Flat

47 (77.0%)

31 (48.4%)

  

 Nodular

7 (11.5%)

23 (35.9%)

  

 Intermediate

7 (11.5%)

10 (15.6%)

  

Final

  

0.007

 

 Flat

45 (73.8%)

31 (48.4%)

  

 Nodular

7 (11.5%)

21 (32.8%)

  

 Intermediate

9 (14.8%)

12 (18.8%)

  
  1. ESD, endoscopic submucosal dissection.
  2. *Post-ESD ulcer healing at 8 weeks was analyzed, excluding 7 patients who did not perform follow-up endoscopy at 8 weeks after ESD (3 patients in combination therapy, 4 patients in tegoprazan monotherapy.
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