Fig. 2 | Scientific Reports

Fig. 2

From: Comparative analysis of cutaneous features of psoriasis in acute and chronic imiquimod-induced mouse models

Fig. 2

Effects of IMQ on the gene expression levels of pro-inflammatory mediators and epidermal markers after ST and LT treatments. Pro-inflammatory mediators (IL-17A (A), IL-1α (B), CXCL3 (C)), AMPs (BD3 (D)) and epidermal markers (KRT6 (E), KRT10 (F), IVL (G), KLK5 (H)) gene expression was assessed by RT-qPCR on total mRNAs from mouse back skin collected 24 h after the last Vaseline or IMQ application, and normalized with GAPDH (ST-Vaseline n = 25, ST-IMQ n = 32, LT-Vaseline n = 28, LT-IMQ n = 26). A Two-Way ANOVA with Bonferroni’s correction was performed to compare each mediator expression after ST and LT treatments either with Vaseline or IMQ.

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