Fig. 6
From: Cooperative role of MDSCs and Tregs in alum-induced alloimmune tolerance in corneal transplantation
Representative anterior segment images of corneal grafts on day 21 post-transplantation. Gross photographs of corneal grafts in each experimental group: syngeneic control (A), alum-treated (B), alum-induced MDSCs combined with Tregs (MDSCs + Tregs) (C), MDSCs alone (D), and PBS-treated allogeneic controls (E).Corneal grafts in the alum-treated and MDSCs + Tregs groups remained clear, with no signs of rejection. In contrast, the MDSC-only group exhibited partial opacity and mild neovascularization, consistent with ongoing immune rejection. The PBS-treated allogeneic group showed complete graft opacity, edema, and extensive neovascularization, indicating rapid and severe rejection. The syngeneic group maintained full graft clarity as expected.
