Table 1 Summary table of compound comparisons.
From: Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis
Treatment | Improvement of fine wrinkle (OR, 95% CI) | Improvement of coarse wrinkle (OR, 95% CI) | Improvement of hyperpigmentation (OR, 95% CI) | Improvement of roughness (OR, 95% CI) | Safety (OR, 95% CI) |
|---|---|---|---|---|---|
Adapalene | 9.29 (0.95, 90.92) | – | – | – | 0.77 (0.04, 13.5) |
Glycolic acid | 2.36 (0.56, 10.06) | 1.29 (0.43, 3.85) | 1.55 (0.11, 22.24) | – | 0.46 (0.11, 2.04) |
Isotretinoin | 116.23 (19.08, 708.19) | – | – | – | 0.27 (0.05, 1.58) |
Retinol | 14.10 (4.80, 41.38) | 2.73 (1.12, 6.68) | 2.60 (0.55, 12.29) | 5.49 (1.46, 20.66) | 0.48 (0.18, 1.33) |
Tazarotene | 3.95 (1.41, 11.10) | 1.84 (1.22, 2.76) | 2.18 (0.61, 7.85) | 1.00 (0.42, 2.37) | 0.26 (0.11, 0.61) |
Topical bakuchiol | 9.40 (0.66, 134.36) | – | – | – | 0.44 (0.02, 8.93) |
Tretinoin | 6.87 (2.88, 15.37) | 1.94 (1.25, 3.01) | 4.78 (1.85, 12.33) | 2.59 (1.35, 4.99) | 0.77 (0.42,1.41) |
