Fig. 4
From: Immune cell subsets in autoimmune polyendocrine syndrome type I
Unsupervised analysis of human whole blood-derived mass cytometry (CyTOF) normalized data on autoimmune polyendocrine syndrome type I (APS-I) patients and healthy controls (HC) for dataset 1. All T cells. (A) Number of T cells from each in dividual. (B) UMAP plots for T cell subsets including eight clusters for APS-I patients and healthy controls. The clusters are manually annotated based on the marker heatmap in Fig S7. (C) Boxplot on T cell subset frequency in each cluster for APS-I patients and healthy controls. (D) MDS-plot for T cell subsets with colours representing the two cohorts of interest. Statistical tests were performed by the EdgeR and limma packages. Th T helper cell, Tc cytotoxic T cell, mem. Memory, TCR, T cell Receptor, gdT, gammadelta T cells.
