Fig. 5
From: Immune cell subsets in autoimmune polyendocrine syndrome type I
Unsupervised analysis of human whole blood-derived mass cytometry (CyTOF) normalized data on autoimmune polyendocrine syndrome type I (APS-I) patients and healthy controls (HC) for dataset 1. All natural killer (NK) cells. (A) Number of NK cells from each in dividual. (B) UMAP plots for NK subsets including eight clusters for APS-I patients and healthy controls. The clusters are manually annotated based on the marker heatmap in Fig S7. (C) Boxplot on NK cell subset frequency in each cluster for APS-I patients and healthy controls. (D) MDS-plot for NK cell subsets with colours representing the two cohorts of interest. Statistical tests were performed by the EdgeR and limma packages.
