Fig. 7

Heatmaps of the identified 19 studies with immune cell characterizations of APS-I patients, which included > 10 patients. (A) T cells. (B) Tregs. (C) B cells. (D) Natural killer (NK) cells. (E) Monocytes and dendritic cells (DCs). The scale goes from 0 to 4, where 0 means significantly lower, 1 means a trend towards lower, 2 means same as healthy donors, 3 means trends towards upregulation, and 4 means statistically significant upregulation. All comparisons are with healthy donors in the respective studies. The x-axis shows the number of studies, and the y-axis denotes the immune subsets. Missing values are white. A more comprehensive overview of the results in all the 29 identified studies is found in Supplementary Table 6. References for this figure. Study 1. This study. Study 2¹⁸. Study 3²¹. Study 4¹⁷. Study 5¹⁵. Study 6²². Study 7²³. Study 8²⁴. Study 9²⁵. Study 10¹⁴. Study 11²⁶. Study 12²⁷. Study 13²⁸. Study 14²⁹. Study 15³⁰. Study 16¹⁹. Study 17³¹. Study 18³². Study 19³³.