Fig. 2 | Scientific Reports

Fig. 2

From: Comparative analysis of clinical features, methylation and immune microenvironment in pediatric and adult papillary craniopharyngiomas: results from a multicenter study

Fig. 2

Difference in histology and proliferation between PPCP and APCP. (A–D) PPCP-specific histology: Pan-layer inflammatory infiltration (A), mucin-ciliated epithelial complexes (B arrows), calcification (C), Rathke’s cyst epithelial migration (D arrows). (E and F) APCP representative H&E. (G and H) Ki-67 spatial dichotomy: Band-like distribution (PPCP) vs. scattered dot-like pattern (APCP). (I) Quantified proliferative disparity (t = 6.146, P < 0.01). Staining markers: Blue arrow-mucin vacuoles, Red arrow-ciliated epithelium, Yellow arrow-pheochromocyte-like cells.

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