Fig. 3

BRAF V600E, β-catenin, and methylation profiles in PPCP and APCP. (A, C) Parenchymal BRAF V600E positivity (stroma-negative) in both groups. (B, D) Pan-cytoplasmic β-catenin expression (nuclear-negative). (E, F) Hierarchical clustering analysis and t-stochastic neighbor embedding analysis revealed no significant difference in the methylation profiles between PPCP and APCP.