Fig. 4 | Scientific Reports

Fig. 4

From: Comparative analysis of clinical features, methylation and immune microenvironment in pediatric and adult papillary craniopharyngiomas: results from a multicenter study

Fig. 4

PD-L1, PD-1 and CD38 expression profiles in PPCP and APCP. (A-B) PD-L1 cytoplasmic localization in tumor parenchyma. (C-D) Absence of PD-1 in parenchyma/stroma. (E) Lower PD-L1 expression in PPCP vs. APCP (t = 4.351, p < 0.01,). (F-H) CD38 stromal expression with higher intensity in PPCP vs. APCP (t = 9.452, p < 0.01). (I) PD-1 stromal detection by immunofluorescence. (J-K) Correlation analysis: PPCP (r = 0.4433, p = 0.1294); APCP (r= − 0.2549, p = 0.020).

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