Fig. 6 | Scientific Reports

Fig. 6

From: LINC00162 silencing enhances sorafenib sensitivity and inhibits thyroid cancer cells progression through modulation of MAPK signaling and apoptosis

Fig. 6

Effect of the LINC00162 silencing combined with sorafenib on apoptosis induction in B-CPAP thyroid cancer cells. (A) Apoptosis rate in various groups evaluated by AnnexinV/PI assay. (B) While LINC00162 siRNA transfection and treatment with sorafenib significantly increased apoptosis rate, the combination of these treatments induced apoptosis more than individual treatments (****p < 0.0001 and ***p < 0.001). (C) DAPI staining to determine chromatin fragmentation.

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