Fig. 1

Theoretical CaM binding motifs in the N- and C-terminus of the human aquaporin homologues. The Calmodulin Target Database26 was used to identify potential CaM binding sites in hAQP0-hAQP12. The location of the putative CaM-binding motifs is highlighted in yellow and score 0–9 is used to indicate the strength of the binding. Additionally, interaction sites to CaM, which has been confirmed by experiments, are highlighted in red.