Fig. 3

KEGG analysis of the up- and down-regulated proteins in SCNECC. A. KEGG enrichment analysis for up-regulated proteins. B. KEGG enrichment analysis for down-regulated proteins. The Y-axis denotes the KEGG pathway, while the X-axis represents the ratio of DEPs to the total number of proteins annotated within each pathway. The coloration of the dots corresponds to the significance level of the adjusted p-value, and the size of the circular markers is scaled to reflect the quantitative abundance of DEPs identified in each pathway.