Fig. 10 | Scientific Reports

Fig. 10

From: Integrative network pharmacology and multi-omics reveal anisodamine hydrobromide’s multi-target mechanisms in sepsis

Fig. 10

Global, Time‐Dependent Feature Importance of the StepCox[forward] + RSF Model Lines represent each gene’s importance over time, measured by changes in dynamic AUC loss. CCL5 consistently shows the highest importance at all time points, with its influence increasing over the course of prediction. FKBP1B, LCK, ARG1, and ELANE also maintain high and stable importance, indicating their sustained contributions to survival risk estimation.

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