Table 4 Cytokines, chemokines and growth factors in cerebrospinal fluid (CSF).

From: Pilot study of cerebrospinal fluid biomarkers reveals inflammatory changes in patients with paranoid schizophrenia

Cerebrospinal fluid (CSF) results

Schizophrenia (n = 35)

Non-inflammatory controls (n = 40)

Inflammatory controls (n = 35)

MCP-1 concentration [pg/ml], mean (SD)

650 (410)

667 (455)

p = 0.862

316 (299)

p < 0.001

IL-8 concentration [pg/ml], mean (SD)

48 (053)

51 (76)

p = 0.602

178 (178)

p = 0.002

sTREM-2 concentration [pg/ml], mean (SD)

4552 (5371)

4677 (4299)

p = 0.384

4324 (3179)

p = 0.529

IL-6 concentration [pg/ml], mean (SD)

2.68 (3.48)

3.38 (8.07)

p = 0.751

1.61 (2.55)

p = 0.215

  1. CSF = cerebrospinal fluid; MCP-1 = monocyte chemoattractant protein 1; IL = interleukin; sTREM-2 = soluble triggering receptor expressed on myeloid cells; SD = standard deviation. The presented p-values reflect the comparison between the corresponding control group (inflammatory or non-inflammatory) and individuals with schizophrenia.
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