Table 1 DPPH free radical scavenging activity of FP1–FP7.

From: Synthesis and evaluation of novel thiohydantoin derivatives for antidiabetic activity using in silico in vitro and in vivo methods

Concentration (µg/mL)

FP1

FP2

FP3

FP4

FP5

FP6

FP7

Ascorbic Acid (Standard)

3.12

12.5 ± 1.1

18.4 ± 1.3

9.2 ± 0.9

22.1 ± 1.5

17.8 ± 1.2

8.5 ± 0.8

7.6 ± 0.7

30.2 ± 1.9

6.25

24.7 ± 1.8

31.3 ± 1.9

18.5 ± 1.4

38.2 ± 2.1

29.6 ± 1.7

16.2 ± 1.1

14.8 ± 1.0

50.6 ± 2.5

12.5

38.1 ± 2.3

47.6 ± 2.4

27.9 ± 1.8

55.7 ± 2.6

44.5 ± 2.3

24.9 ± 1.6

21.5 ± 1.4

68.9 ± 2.8

25

51.5 ± 2.7

62.9 ± 2.8

38.3 ± 2.1

71.6 ± 3.0

58.7 ± 2.6

36.4 ± 2.2

30.2 ± 1.8

82.3 ± 3.1

50

58.9 ± 2.9

74.5 ± 3.1

45.7 ± 2.3

81.2 ± 3.5

69.3 ± 2.9

44.7 ± 2.5

39.5 ± 2.0

89.6 ± 3.3

100

63.4 ± 3.0

79.8 ± 3.2

51.2 ± 2.5

85.9 ± 3.7

73.1 ± 3.1

49.8 ± 2.6

43.7 ± 2.3

94.2 ± 3.5

200

67.3 ± 3.2

82.6 ± 3.3

55.8 ± 2.7

87.4 ± 3.9

78.9 ± 3.3

53.6 ± 2.8

47.2 ± 2.5

96.8 ± 3.7

  1. (Expressed as % inhibition at different concentrations, compared to Ascorbic Acid as the standard.).