Table 3 Alpha glucosidase Inhibition of newly synthesized Thiohydantoin derivatives.

From: Synthesis and evaluation of novel thiohydantoin derivatives for antidiabetic activity using in silico in vitro and in vivo methods

Serial no

Sample name

%Inhibition (200 µg/ml) % (Mean ± SD)

IC50 (µg/ml)

(Mean ± SD)

1

FP1

45.68 ± 1.12

150.85 ± 4.26

2

FP2

48.12 ± 0.94

138.60 ± 3.78

3

FP3

29.35 ± 1.08

N/A

4

FP4

51.37 ± 1.25

129.40 ± 3.41

5

FP5

33.18 ± 0.87

N/A

6

FP6

36.44 ± 1.03

N/A

7

FP7

27.26 ± 0.91

N/A

8

Miglitol

87.92 ± 1.09

85.30 ± 2.98

9

DMSO

1.62 ± 0.31

N/A

  1. Note: Sample concentration = 200 µg/ml, Positive control = Miglitol (50 µg/ml), Negative control = DMSO, N/A = Not applicable, “---” = No α-glucosidase inhibition activity.
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