Table 4 Alpha amylase Inhibition of newly synthesized Thiohydantoin derivatives.

From: Synthesis and evaluation of novel thiohydantoin derivatives for antidiabetic activity using in silico in vitro and in vivo methods

Serial no

Sample name

%Inhibition (200 µg/ml) % (Mean ± SD)

IC50 (µg/ml)

(Mean ± SD)

1

FP1

18.43 ± 1.02

N/A

2

FP2

48.37 ± 0.96

140.25 ± 4.11

3

FP3

21.22 ± 0.89

N/A

4

FP4

54.62 ± 1.17

128.90 ± 3.68

5

FP5

50.87 ± 1.05

135.45 ± 3.93

6

FP6

46.92 ± 0.98

145.30 ± 4.42

7

FP7

23.14 ± 1.14

N/A

8

Acarbose

92.23 ± 1.08

75.70 ± 2.55

9

DMSO

1.47 ± 0.28

N/A

  1. Note: Sample concentration = 200 µg/ml, Positive control = Acarbose (50 µg/ml); Negative control = DMSO,.
  2. N/A = Not applicable, --- = no α-amylase inhibition activity,.
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