Table 1 Relationship between the pretreatment AFR and clinicopathological features.

From: Preoperative albumin-to-fibrinogen ratio as a predictor of postoperative hospital stay in locally advanced esophageal squamous cell carcinoma after neoadjuvant therapy

 

Total

High-AFR

Low-AFR

p-value

Total(n)

135

66

69

 

Sex(n)

   

0.055

Male

111

50

61

 

Female

24

16

8

 

Age(years, median)

60 (54–65)

58.50 (51–63)

63 (56–65)

0.029

BMI(kg/m2, median)

21.67 (19.98–23.51)

21.396 (19.489–23.009)

21.969 (20.389–23.954)

0.171

MIE

   

NA

Yes

135

66

69

 

No

0

0

0

 

Surgical approaches

   

0.205

Ivor-Lewis

77

34

43

 

McKeown

58

32

26

 

Operating time (min)

314 (263–365)

309 (264–354)

318 (263–373)

0.472

Dissected fields

   

0.583

2-field

89

42

47

 

3-field

46

24

22

 

Harvested mediastinal lymph nodes

18.7 (15.2–22.6)

19.6 (15.9–23.3)

18.2 (14.1–22.3)

0.132

Amount of bleeding (ml)

131 (57–205)

127 (42–212)

136 (65–207)

0.34

Respiratory complications

22

10

12

0.725

Cardiovascular complications

12

5

7

0.6

Other complications

6

3

3

0.956

Smoking disease

   

0.888

Yes

81

40

41

 

No

54

26

28

 

Hepatic disease

   

0.188

Fatty liver

19

12

7

 

Hepatocirrhosis

13

4

9

 

Hepatitis B

24

9

15

 

No

79

41

38

 

Respiratory diseases

   

0.232

Yes

18

6

12

 

No

117

60

57

 

High blood pressure

   

0.067

Yes

20

6

14

 

No

115

60

55

 

Diabetes

   

0.975

Yes

2

1

1

 

No

133

65

68

 

Tumor localization

   

0.808

Upper

13

6

7

 

Middle

78

40

38

 

Lower

44

20

24

 

Erythrocyte count (× 1012/L, median)

4.17 ± 0.56

4.17 ± 0.54

4.17 ± 0.58

0.927

Platelet counts (× 109/L, median)

222.15 ± 62.85

200.7 ± 56.786

242.90 ± 61.860

 < 0.001

Albumin (g/L)

41.15(38.375–43.575)

42.6 (40.2–44.7)

39.45 (37.475–42.4)

 < 0.001

Globulin (g/L)

29.864 ± 4.62

29.20 ± 4.19

30.505 ± 4.95

0.179

Neutrophil counts (× 109/L, median)

3.275 (2.725–4.433)

3.12 (2.65–4.18)

3.615 (2.935–5.0675)

0.041

Lymphocyte count (× 109/L, median)

1.744 ± 0.60

1.6985 ± 0.576

1.7876 ± 0.624

0.353

Monocyte count (× 109/L, median)

0.465 (0.37–0.60)

0.42 (0.3325–0.515)

0.50 (0.395–0.66)

0.004

CREA (μmol/L, median)

75 (62.75–84)

71.5 (60–84)

75.5 (66–84)

0.305

Na + (mmol/L, median)

140.84 ± 2.457

141.565 ± 2.318

140.14 ± 2.401

0.002

Cholesterol (g/L)

5.2 (4.4250–6.2325)

5.155 (4.415–5.8875)

5.26 (4.4125–6.6525)

0.37

Fibrinogen (g/L)

3.965 (3.385–4.81)

3.41(3–3.8)

4.785(4.145–5.73)

 < 0.000

D-dimer (ug/mL)

0.625 (0.367–1.065)

0.59(0.35–0.9075

0.71(0.4175–1.7725)

0.074

T

   

0.209

0

9

3

6

 

1

18

13

5

 

2

26

14

12

 

3

75

33

42

 

4

7

3

4

 

N

   

0.18

0

62

29

33

 

1

46

25

21

 

2

23

10

13

 

3

4

2

2

 

Discharge destination

   

0.964

Home

131

64

67

 

Rehabilitation institutions

4

2

2

 

Oral intake on the day of discharge (kcal/d)

1017 (829–1168)

1050 (865–1235)

980 (765–1195)

0.107

Duration of jejunal feeding before discharge (day)

9.7 (7.2–12.4)

8.5 (6.4–10.6)

11.3 (7.7–14.9)

 < 0.001

  1. AFR, albumin-to-fibrinogen ratio; BMI, body mass index; CREA, creatinine. Data completeness: 99.3% for respiratory comorbidities, 94.1% for T staging, 97.03% for N staging, and 68.9% for tumor differentiation grade.