Fig. 3

Results of the SAR investigation on E. coli (K-12 MG1655). The graphs show normalised optical density (O.D. 600 nm) measurements of the supernatant, enabling comparative analysis of flocculation activity for each compound. Measurements were performed in triplicate. The effect of the solvent (5.9% DMSO) is included as a negative control. (a) Compounds 1–5, initially synthesised and screened, (b) results for compounds 6–8, synthesised in a second phase of the SAR study.