Fig. 6 | Scientific Reports

Fig. 6

From: Targeting FBXL5 to induce ferroptosis and reverse oxaliplatin resistance in iron-rich colorectal cancer

Fig. 6

FBXL5 knockdown suppresses proliferation and migration while enhancing oxaliplatin sensitivity in HCT−116/OXA cells. (A)CCK−8 assay to determine the proliferation levels of HCT−116/OXA cells after FBXL5 modulation. (B) Transwell migration assay to evaluate the effect of FBXL5 modulation on the migratory ability of HCT−116/OXA cells. (C) Colony formation assay to assess the effect of FBXL5 modulation on the proliferative ability of HCT−116/OXA cells. (D) Dose-response curves showing the chemosensitivity of HCT−116/OXA cells to oxaliplatin after FBXL5 modulation.

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