Table 1 Percentage of cytotoxicity of different concentrations of the synthesized compounds on cancer and normal cell lines.

From: Synthesis of heterocycle based carboxymethyl cellulose conjugates as novel anticancer agents targeting HCT116, MCF7, PC3 and A549 cells

 

Cell line

 

HCT-116

A549

Dose

(µg/ml)

7b

7c

7d

4b

7b

7c

7d

4b

100

42.09

80.66*

50.36

90.56*

.

77.43*

.

80.93*

50

39.46

71.96*

45.53

85.50*

.

77.10*

.

75.73*

25

31.13

69.26*

38.09

82.12*

.

75.61*

.

66.61*

12.5

20.66

68.53*

25.46

76.53*

.

67.85*

.

60.04*

 

PC3

RPE-1

Dose

(µg/ml)

7b

7c

7d

4b

7b

7c

7d

4b

100

40.98

62.56*

38.16

95.65*

18.06

52.28

12.14

58.13

50

35.06

59.17*

23.16

65.28*

12.54

45.25

11.29

49.43

25

25.40

46.43*

4.77

58.47*

8.61

38.66

10.76

44.43

12.5

20.74

39.51*

4.27

43.63*

3.27

29.23

4.21

37.33

  1. * p < 0.01 when compared with untreated cells.
Back to article page