Table 5 Similarities in common ADRs to two ADHD drugs.
System organ classes | ADRs | Signal N |
|---|---|---|
Cardiac disorders | Extrasystoles, Palpitations, Cardiac arrest, Tachycardia, Cardiac disorder | 5 |
Ear and labyrinth disorders | Tinnitus, Hyperacusis, Vertigo | 3 |
Eye disorders | Vision blurred, Mydriasis, Photophobia, Visual impairment | 4 |
Gastrointestinal disorders | Nausea, Abdominal pain, Dysphagia, Diarrhea, Dyspepsia, Gastrointestinal disorder, Dry mouth, Vomiting, Constipation, Abdominal distension, Abdominal pain upper, Retching | 11 |
General disorders and administration site conditions | Feeling abnormal, Adverse event, Pain, Withdrawal syndrome, Drug interaction, Condition aggravated, Malaise, Drug ineffective, Fatigue, Asthenia, Crying, Chest pain | 12 |
Immune system disorders | Hypersensitivity | 1 |
Injury, poisoning and procedural complications | Overdose, Wrong technique in product usage process, Product dose omission issue, Product use in unapproved indication, Off label use, Fall, Product use issue | 7 |
Investigations | Blood pressure increased, Alanine aminotransferase increased, Weight decreased, Aspartate aminotransferase increased, Heart rate increased | 5 |
Metabolism and nutrition disorders | Decreased appetite, Dehydration | 2 |
Musculoskeletal and connective tissue disorders | Myalgia, Muscle spasms, Muscle twitching, Rhabdomyolysis, Musculoskeletal stiffness, Back pain | 6 |
Nervous system disorders | Dystonia, Tremor, Dizziness, Seizure, Somnolence, Psychomotor hyperactivity, Headache, Loss of consciousness, Speech disorder, Paraesthesia, Disturbance in attention, Migraine, Lethargy | 13 |
Product issues | Product physical issue, Product availability issue | 2 |
Psychiatric disorders | Anger, Completed suicide, Suicidal ideation, Mood swings, Agitation, Insomnia, Anxiety, Panic attack, Aggression, Depression, Sleep disorder, Irritability, Confusional state | 13 |
Renal and urinary disorders | Urinary incontinence | 1 |
Reproductive system and breast disorders | Erectile dysfunction | 1 |
Respiratory, thoracic and mediastinal disorders | Dyspnoea | 1 |
Skin and subcutaneous tissue disorders | Rash erythematous,Erythema,Pruritus,Rash,Hyperhidrosis,Eczema,Urticaria | 7 |
Social circumstances | Loss of personal independence in daily activities, Impaired work ability | 2 |
Vascular disorders | Raynaud’s phenomenon, Hypertension, Hypotension | 3 |
