Fig. 2 | Scientific Reports

Fig. 2

From: Role of T cell exhaustion and tissue-resident memory T cells in the expression and prognosis of colorectal cancer

Fig. 2

Characterisation of PD−1, Tim−3, CD39 and CD103 Expression in T/NK Cell Subsets (A) UMAP visualisation of T/NK cell subsets.(B) Dot plot displaying expression levels and frequencies of key genes across T/NK cell subtypes. (C) UMAP plots showing T/NK cell distribution and transcriptomic profiles across Stages I–IV. (D–E) Bar plots illustrating dynamic changes and relative proportions of T cell subsets across Stages I to IV.(F) UMAP plots showing expression patterns of PDCD1, HAVCR2, ENTPD1, and ITGAE.(G–H) Differentiation trajectory of CD8⁺ T cells visualised by cluster identity (G) and pseudotime (H).UMAP, Uniform Manifold Approximation and Projection; T, T cells; NK, natural killer cells; PDCD1, programmed cell death protein 1; HAVCR2, hepatitis A virus cellular receptor 2; ENTPD1, ectonucleoside triphosphate diphosphohydrolase 1; ITGAE, integrin alpha E.

Back to article page