Table 2 Analyses for the assay performance in the UC detection.
All UC | High-grade UC | Low-grade UC | Non-invasive UC | Invasive UC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
vs. | vs. | vs. | vs. | vs. | ||||||
Healthy | Non-UC | Healthy | Non-UC | Healthy | Non-UC | Healthy | Non-UC | Healthy | Non-UC | |
Sensitive, % | 85.2 | 85.2 | 92.4 | 92.4 | 80.0 | 80.0 | 70.0 | 70.0 | 94.1 | 94.1 |
Specificity, % | 100.0 | 90.0 | 100.0 | 90.0 | 100.0 | 90.0 | 100.0 | 89.4 | 100.0 | 89.4 |
PPVa, % | 100.0 | 79.3 | 100.0 | 76.4 | 100.0 | 34.8 | 100.0 | 52.2 | 100.0 | 74.1 |
NPVb, % | 79.8 | 93.1 | 90.8 | 97.1 | 95.2 | 98.5 | 84.0 | 94.8 | 94.0 | 98.2 |
Accuracy, % | 90.7 | 88.5 | 95.7 | 90.6 | 96.0 | 89.4 | 88.4 | 78.7 | 97.0 | 90.6 |
AUC | 0.926 | 0.876 | 0.962 | 0.912 | 0.900 | 0.850 | 0.850 | 0.797 | 0.971 | 0.917 |
