Table 2 Index stroke, treatment, and outcome.

From: Dynamic cerebral autoregulation during and 3 months after endovascular treatment in large vessel occlusion stroke

 

All enrolled (n = 77)

Follow-up (n = 54)

No follow-up (n = 23)

P-value

Ischemic hemisphere, right side, n (%)

44 (57.1)

32 (59.3)

12 (52.2)

0.746

Onset, n (%)

   

0.387

 Wake-up

19 (24.7)

11 (20.4)

8 (34.8)

 

 Unwitnessed

10 (13.0)

7 (13.0)

3 (13.0)

 

Stroke etiology, n (%)

   

0.397

 Large-artery atherosclerosis

28 (36.4)

21 (38.9)

7 (30.4)

 

 Cardio-aortic embolism

27 (35.1)

18 (33.3)

9 (39.1)

 

 Other causes (dissection)

5 (6.5)

2 (3.7)

3 (13)

 

 Undetermined causes

17 (22.1)

13 (24.1)

4 (17.4)

 

IVT, n (%)

35 (45.5)

28 (51.9)

7 (30.4)

0.133

Occluded artery, n (%)

    

 ICA

6 (7.8)

4 (7.4)

2 (8.7)

1.000

 ICA-top

14 (18.2)

10 (18.5)

4 (17.4)

1.000

 ICA-tandem

12 (15.6)

11 (20.4)

1 (4.3)

0.095

 M1

50 (64.9)

36 (66.7)

14 (60.9)

0.795

 M2

23 (29.9)

17 (31.5)

6 (26.1)

0.787

 ACA

8 (10.4)

5 (9.3)

3 (13.0)

0.690

 BA

5 (6.5)

2 (3.7)

3 (13.0)

0.154

 PCA

3 (3.9)

3 (5.6)

1 (4.3)

1.000

ASPECTS / PC-ASPECTS, median (IQR)

    

 Before EVT

 24-h

8 (6; 10)

7 (5; 8)

9 (7; 10)

7 (6; 8.75)

7 (6; 8.5)

5 (3; 7)

0.081

0.002

Successful reperfusion (mTICI ≥ 2b), n (%)

69 (89.6)

51 (94.4)

18 (78.3)

0.047

Last-known-well to reperfusion*

294 (202; 625)

280 (178; 523)

344 (283; 887)

0.033

NIHSS, median (IQR)

    

 Before EVT

16.5 (11; 21.25)

15 (9.25; 20)

20 (14.25; 23.75)

0.026

 24-h

6 (3; 13.25)

5 (3; 9)

16 (8.5; 20.75)

 < 0.001

 90-day

N/A

2 (1; 4)

N/A

 

90-day mRS, median (IQR)

3 (1; 4)

2 (1; 3)

6 (4; 6)

 < 0.001

90-day independence, n (%)

36 (46.8)

32 (59.2)

4 (16.7)

0.001

Vascular events, n (%)

5 (6.5)

2 (3.7)

3 (13)

0.154

All-cause mortality, n (%)

    

 90-day

13 (16.9)

0 (0)

13 (56.5)

 < 0.001

 1 year

19 (24.7)

4 (7.4)

15 (65.2)

 < 0.001

  1. IVT: Intravenous thrombolysis. ICA: Internal carotid artery. M1: First part of middle cerebral artery. M2: Second part of middle cerebral artery. ACA: Anterior cerebral artery. BA: Basilar artery. PCA: Posterior cerebral artery. ASPECTS: Alberta Stroke Program Early CT Score. PC-ASPECTS: Posterior circulation ASPECTS. mTICI: Modified treatment in cerebral infarction. NIHSS: National Institutes of Health Stroke Scale. EVT: Endovascular treatment. *: In case of mTICI 0, defined as time of abandoning EVT efforts. †: Modified Rankin Scale 0–2. ‡: Defined as recurrent stroke, myocardial infarction, or surgery for peripheral artery disease at 90-day FU.