Table 1 Performance of PS3N using single similarity matrices based on protein sequences.

From: PS3N: leveraging protein sequence-structure similarity for novel drug-drug interaction discovery

Distance metric

Precision

Recall

F-measure

AUC

Accuracy

L AS

0.9199

0.9419

0.9308

0.9673

0.9081

JSD AS

0.8837

0.8667

0.8751

0.9181

0.8377

CS AS

0.8799

0.9093

0.8943

0.9315

0.8590

L EWAS

0.9499

0.9638

0.9568

0.9832

0.9429

JSD EWAS

0.9406

0.8835

0.9112

0.9559

0.8870

CS EWAS

0.9523

0.9632

0.9578

0.9833

0.9443

  1. *L = Levenshtein, JSD = JS Divergence, CS = Cosine, AS = Average Similarity, EWAS = Exponential Weighted Average Similarity
Back to article page