Fig. 2

Association of anti-PRMT5 antibodies with clinical characteristics of RA. (A) Comparisons of serum levels of anti-PRMT5 antibodies between RA patients with no ILD or indeterminate ILD (RA-ILD: 0 + 1, n = 48) and RA patients with moderate or advanced ILD (RA-ILD: 2 + 3, n = 39). (B) Spearman correlation between anti-PRMT5 antibodies and ILD grades. Correlation coefficient (r) and p-value are indicated. Comparisons of serum levels of anti-PRMT5 antibodies between RF-negative RA and RF-positive RA patients (C) and between anti-CCP-negative and anti-CCP-positive RA patients (D). ns, not significant, ****p < 0.0001.